SOLUTION —
Given, $\quad x=-5+2 \sqrt{-4}$
$\Rightarrow (x+5)^2 =-16$
$\Rightarrow x^2+10 x+41 =0$
$\therefore$ Given expression can be rewritten as
$\left(x^2+10 x+41\right)\left(x^2-x+4\right)-160$
$=0 \times\left(x^2-x+4\right)-160=-160$
So, The correct option will be (C).